SLPI anticorps (AA 60-110)

N° du produit ABIN6990761

L’anticorps Lapin Polyclonal anti-SLPI a été validé pour WB, ELISA et IHC (p). Il convient pour détecter SLPI dans des échantillons de Humain et Souris.

Aperçu rapide pour SLPI anticorps (AA 60-110) (ABIN6990761)

Antigène: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLPI est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SLPI anticorps

Épitope: AA 60-110

Purification: SLPI Antibody is affinity chromatography purified via peptide column.

Immunogène: SLPI antibody was raised against a 17 amino acid synthetic peptide from near the center of human SLPI. The immunogen is located within amino acids 60 - 110 of SLPI.

Isotype: IgG

Information d'application

Indications d'application: SLPI antibody can be used for detection of SLPI by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SLPI Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SLPI antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SLPI

Antigène: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Autre désignation: SLPI

Sujet: SLPI Antibody: Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-κ,B activation by inhibiting Iκ,B degradation in the cytoplasm and competing for NF-κ,B binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.

Poids moléculaire: Predicted: 15 kDa

Observed: 19 kDa

ID gène: 6590

UniProt: P03973