CDNF anticorps (C-Term)

N° du produit ABIN6990801

Cet anticorps anti-CDNF est un anticorps Lapin Polyclonal détectant CDNF dans WB, ELISA, IHC (p) et IF. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour CDNF anticorps (C-Term) (ABIN6990801)

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDNF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-CDNF anticorps

Épitope: C-Term

Specificité: This antibody does not cross-react with MANF.

Purification: CDNF Antibody is affinity chromatography purified via peptide column.

Immunogène: CDNF antibody was raised against a 9 amino acid synthetic peptide from near the carboxy terminus of human CDNF. The immunogen is located within the last 50 amino acids of CDNF.

Isotype: IgG

Information d'application

Indications d'application: CDNF antibody can be used for detection of CDNF by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CDNF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CDNF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CDNF

Antigène: CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))

Autre désignation: CDNF

Sujet: CDNF Antibody: The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist.

ID gène: 441549

UniProt: Q49AH0