Cathelicidin anticorps (AA 50-100)

N° du produit ABIN6990841

Cet anticorps Lapin Polyclonal détecte spécifiquement Cathelicidin dans WB, ELISA, IHC (p) et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Cathelicidin anticorps (AA 50-100) (ABIN6990841)

Antigène: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathelicidin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-Cathelicidin anticorps

Épitope: AA 50-100

Purification: Cathelicidin Antibody is affinity chromatography purified via peptide column.

Immunogène: Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the center of the human Cathelicidin. The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Isotype: IgG

Information d'application

Indications d'application: Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Cathelicidin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Cathelicidin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Cathelicidin

Antigène: Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))

Autre désignation: Cathelicidin

Sujet: Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Poids moléculaire: Predicted: 19 kDa

Observed: 18 kDa

ID gène: 820

NCBI Accession: NP_004336

UniProt: P49913

Pathways: Cellular Response to Molecule of Bacterial Origin