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RIMS2 anticorps (AA 30-80)
RIMS2
Reactivité: Humain
ELISA, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN6990845
Détail du produit anti-RIMS2 anticorps
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Antigène
Voir toutes RIMS2 Anticorps
RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Épitope
Tous les épitopes à travers RIMS2 Anticorps.
AA 30-80
Reactivité
Toutes les réactivités sur RIMS2 Anticorps
Humain
Hôte
Toutes les hôtes sur RIMS2 Anticorps
Lapin
Clonalité
Toutes les clonalités sur RIMS2 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers RIMS2 Anticorps
Cet anticorp RIMS2 est non-conjugé
Application
Tous les applications à travers RIMS2 Anticorps.
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
RIM2 Antibody is affinity chromatography purified via peptide column.
Immunogène
RIM2 antibody was raised against a 16 amino acid peptide near the carboxy terminusof human RIM2. The immunogen is located within amino acids 30 - 80 of RIM2.
Isotype
IgG
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Information d'application
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Indications d'application
RIM2 antibody can be used for detection of RIM2 by immunohistochemistry at 5 μ,g/mL. Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
1 mg/mL
Buffer
RIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C,4 °C
Stockage commentaire
RIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Détails sur RIMS2
(cache)
Antigène
RIMS2
(Regulating Synaptic Membrane Exocytosis 2 (RIMS2))
Autre désignation
RIM2 (RIMS2 Produits )
Synonymes
anticorps OBOE, anticorps RAB3IP3, anticorps RIM2, anticorps 2810036I15Rik, anticorps AW048769, anticorps Rab3ip2, anticorps Rim2(+40A), anticorps Rim2(+44A), anticorps Rim2(+4A), anticorps Serg2, anticorps Syt3-rs, anticorps mKIAA0751, anticorps Nim2, anticorps Rim2, anticorps RIMS2, anticorps MGC159469, anticorps rims2, anticorps zgc:73064, anticorps drs, anticorps drsp, anticorps mema, anticorps np-a, anticorps pinin, anticorps pnn, anticorps pnn-a, anticorps pnn-b, anticorps sdk3, anticorps regulating synaptic membrane exocytosis 2, anticorps regulating synaptic membrane exocytosis 2a, anticorps pinin, desmosome associated protein S homeolog, anticorps RIMS2, anticorps Rims2, anticorps rims2a, anticorps pnn.S
Sujet
RIM2 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins necessary for neuronal transmission and plasticity. RIM1 and RIM2 proteins are expressed in overlapping but distinct patterns throughout the brain. While the ablation of either gene was not lethal in mice, the deletion of both resulted in postnatal mortality. This lethality is due to a defect in neurotransmitter release, synapses without RIM proteins can still release neurotransmitters but are unable to do so in response to normal Ca2+ triggers. Like RIM1, RIM2 is thought to be an effector protein for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner.
Poids moléculaire
Predicted: 148 kDa
ID gène
9699
NCBI Accession
NP_001093587
UniProt
Q9UQ26
Pathways
Hormone Transport , Synaptic Vesicle Exocytosis
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