RIMS3 anticorps (N-Term)

N° du produit ABIN6990855

Cet anticorps anti-RIMS3 est un anticorps Lapin Polyclonal détectant RIMS3 dans WB, ELISA, IHC (p) et IF. Adapté pour Humain et Souris.

Aperçu rapide pour RIMS3 anticorps (N-Term) (ABIN6990855)

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RIMS3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-RIMS3 anticorps

Épitope: AA 60-110, N-Term

Specificité: This antibody is predicted to have no cross-reactivity to other Rim proteins.

Purification: Rim3 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rim3 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Rim3. The immunogen is located within amino acids 60 - 110 of Rim3.

Isotype: IgG

Information d'application

Indications d'application: Rim3 antibody can be used for detection of Rim3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rim3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Rim3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur RIMS3

Antigène: RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))

Autre désignation: Rim3

Sujet: Rim3 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.

ID gène: 9783

NCBI Accession: NP_055562

UniProt: Q9UJD0

Pathways: Stem Cell Maintenance, Synaptic Vesicle Exocytosis