BAIAP3 anticorps (N-Term)

N° du produit ABIN6990870

Cet anticorps anti-BAIAP3 est un anticorps Lapin Polyclonal détectant BAIAP3 dans ELISA, WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour BAIAP3 anticorps (N-Term) (ABIN6990870)

Antigène: BAIAP3 (BAI1-Associated Protein 3 (BAIAP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAIAP3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-BAIAP3 anticorps

Épitope: AA 60-110, N-Term

Specificité: BAP3 is known to have two isoforms, this BAP3 antibody will recognize only isoform 2. Lower molecular weight bands may represent cleavage or degradation products.

Purification: BAP3 Antibody is affinity chromatography purified via peptide column.

Immunogène: BAP3 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human BAP3. The immunogen is located within amino acids 60 - 110 of BAP3.

Isotype: IgG

Information d'application

Indications d'application: BAP3 antibody can be used for the detection of BAP3 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BAP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BAIAP3

Antigène: BAIAP3 (BAI1-Associated Protein 3 (BAIAP3))

Autre désignation: BAP3

Sujet: BAP3 Antibody: BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family. BAP3 is predominantly expressed in the brain and possess high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release. Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.

ID gène: 8938

NCBI Accession: NP_001273393

UniProt: O94812