NIPSNAP (C-Term) anticorps

N° du produit ABIN6990878

L’anticorps anti-NIPSNAP Polyclonal Lapin est utilisé pour la détection de NIPSNAP dans des échantillons de Humain, Souris et Rat. Il a été validé pour ELISA, WB, IF et IHC (p).

Aperçu rapide pour NIPSNAP (C-Term) anticorps (ABIN6990878)

Antigène: NIPSNAP

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Épitope: C-Term

Purification: NIPSNAP Antibody is affinity chromatography purified via peptide column.

Immunogène: NIPSNAP antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human NIPSNAP. The immunogen is located within the last 50 amino acids of NIPSNAP.

Isotype: IgG

Information d'application

Indications d'application: NIPSNAP antibody can be used for the detection of NIPSNAP by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: NIPSNAP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: NIPSNAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détail du antigène

Antigène: NIPSNAP

Sujet: NIPSNAP Antibody: NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

ID gène: 8508

NCBI Accession: NP_003625

UniProt: Q9BPW8