VGF anticorps (C-Term)

N° du produit ABIN6990908

L’anticorps Lapin Polyclonal anti-VGF a été validé pour WB, ELISA, IHC (p) et IF. Il convient pour détecter VGF dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour VGF anticorps (C-Term) (ABIN6990908)

Antigène: VGF (VGF Nerve Growth Factor Inducible (VGF))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VGF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-VGF anticorps

Épitope: C-Term

Purification: VGF Antibody is affinity chromatography purified via peptide column.

Immunogène: VGF antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human VGF. The immunogen is located within the last 50 amino acids of VGF.

Isotype: IgG

Information d'application

Indications d'application: VGF antibody can be used for detection of VGF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VGF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VGF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur VGF

Antigène: VGF (VGF Nerve Growth Factor Inducible (VGF))

Autre désignation: VGF

Sujet: VGF Antibody: VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.

Poids moléculaire: Predicted: 68 kDa

Observed: 70 kDa 

ID gène: 7425

NCBI Accession: NP_003369

UniProt: O15240

Pathways: Hormone Transport, Carbohydrate Homeostasis