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DLGAP1 anticorps (AA 640-690)

L’anticorps Lapin Polyclonal anti-DLGAP1 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter DLGAP1 dans des échantillons de Humain, Rat et Souris.
N° du produit ABIN6990914

Aperçu rapide pour DLGAP1 anticorps (AA 640-690) (ABIN6990914)

Antigène

Voir toutes DLGAP1 Anticorps
DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

Reactivité

  • 45
  • 15
  • 14
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 35
  • 12
  • 1
Lapin

Clonalité

  • 36
  • 12
Polyclonal

Conjugué

  • 20
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DLGAP1 est non-conjugé

Application

  • 18
  • 13
  • 13
  • 12
  • 9
  • 8
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 640-690

    Specificité

    At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.

    Purification

    SAPAP1 Antibody is affinity chromatography purified via peptide column.

    Immunogène

    SAPAP1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human SAPAP1. The immunogen is located within amino acids 640 - 690 of SAPAP1.

    Isotype

    IgG
  • Indications d'application

    SAPAP1 antibody can be used for detection of SAPAP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    SAPAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C,4 °C

    Stockage commentaire

    SAPAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène

    DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))

    Autre désignation

    SAPAP1

    Sujet

    SAPAP1 Antibody: SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM).

    ID gène

    9229

    NCBI Accession

    NP_004737

    UniProt

    O60500
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