SATB2 anticorps (C-Term)

N° du produit ABIN6990917

L’anticorps Lapin Polyclonal anti-SATB2 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter SATB2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SATB2 anticorps (C-Term) (ABIN6990917)

Antigène: SATB2 (SATB Homeobox 2 (SATB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SATB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SATB2 anticorps

Épitope: AA 570-620, C-Term

Specificité: At least two isoforms of SATB2 are known to exist. This SATB2 antibody will not cross-react with SATB1.

Purification: SATB2 Antibody is affinity chromatography purified via peptide column.

Immunogène: SATB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human SATB2. The immunogen is located within amino acids 570 - 620 of SATB2.

Isotype: IgG

Information d'application

Indications d'application: SATB2 antibody can be used for detection of SATB2 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SATB2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SATB2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SATB2

Antigène: SATB2 (SATB Homeobox 2 (SATB2))

Autre désignation: SATB2

Sujet: SATB2 Antibody: Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development.

ID gène: 23314

UniProt: Q9UPW6