TMC8 anticorps (N-Term)

N° du produit ABIN6990929

Détail du produit anti-TMC8 anticorps

Antigène: TMC8 (Transmembrane Channel-Like 8 (TMC8))

Épitope: AA 50-100, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMC8 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least two isoforms of EVER2 are known to exist, this antibody will only recognize the larger isoform. EVER2 has no cross-reactivity to EVER1.

Purification: EVER2 Antibody is affinity chromatography purified via peptide column.

Immunogène: EVER2 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human EVER2. The immunogen is located within amino acids 50 - 100 of EVER2.

Isotype: IgG

Information d'application

Indications d'application: EVER2 antibody can be used for detection of EVER2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: EVER2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: EVER2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TMC8

Antigène: TMC8 (Transmembrane Channel-Like 8 (TMC8))

Autre désignation: EVER2 (TMC8 Produits)

Synonymes: anticorps EV2, anticorps EVER2, anticorps EVIN2, anticorps Ever2, anticorps mFLJ00400, anticorps transmembrane channel like 8, anticorps transmembrane channel-like 8, anticorps transmembrane channel-like gene family 8, anticorps TMC8, anticorps Tmc8

Sujet: EVER2 Antibody: Epidermodysplasia verruciformis (EV) is an autosomal recessive genodermatosis associated with a high risk of skin cancers resulting from a high susceptibility to infection by specific human papillomaviruses. Mutations in two homologous genes EVER1 and EVER2 cause the majority of EV cases. These two proteins form a complex and interact with the zinc transporter ZnT-1 in the endoplasmic reticulum. Cells lacking EVER2 accumulated higher levels of zinc in the nucleolus and nucleus compare to those cells with and intact EVER2 gene, indicating that one role of EVER2 is to regulate the intracellular distribution of zinc.

ID gène: 147138

UniProt: Q8IU68