GDF6 anticorps (C-Term)

N° du produit ABIN6990939

Cet anticorps anti-GDF6 est un anticorps Lapin Polyclonal détectant GDF6 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour GDF6 anticorps (C-Term) (ABIN6990939)

Antigène: GDF6 (Growth Differentiation Factor 6 (GDF6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GDF6 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GDF6 anticorps

Épitope: AA 320-370, C-Term

Purification: GDF6 Antibody is affinity chromatography purified via peptide column.

Immunogène: GDF6 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human GDF6. The immunogen is located within amino acids 320 - 370 of GDF6.

Isotype: IgG

Information d'application

Indications d'application: GDF6 antibody can be used for detection of GDF6 by Western blot at 0.5 to 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GDF6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GDF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GDF6

Antigène: GDF6 (Growth Differentiation Factor 6 (GDF6))

Autre désignation: GDF6

Sujet: GDF6 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.

ID gène: 392255

NCBI Accession: NP_001001557

UniProt: Q6KF10