ALDH3A2 anticorps (C-Term)

N° du produit ABIN6990973

Cet anticorps Lapin Polyclonal détecte spécifiquement ALDH3A2 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ALDH3A2 anticorps (C-Term) (ABIN6990973)

Antigène: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH3A2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ALDH3A2 anticorps

Épitope: C-Term

Specificité: At least four isoforms of Aldh3A2 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A1.

Purification: Aldh3A2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Aldh3A2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Aldh3A2. The immunogen is located within the last 50 amino acids of Aldh3A2.

Isotype: IgG

Information d'application

Indications d'application: Aldh3A2 antibody can be used for detection of Aldh3A2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Aldh3A2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Aldh3A2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ALDH3A2

Antigène: ALDH3A2 (Aldehyde Dehydrogenase 3 Family, Member A2 (ALDH3A2))

Autre désignation: Aldh3A2

Sujet: Aldh3A2 Antibody: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.

ID gène: 224

NCBI Accession: NP_001026976

UniProt: P51648