SPRED2 anticorps (AA 140-190)

N° du produit ABIN6990997

Détail du produit anti-SPRED2 anticorps

Antigène: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Épitope: AA 140-190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPRED2 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.

Purification: Spred2 Antibody is affinity chromatography purified via peptide column.

Immunogène: Spred2 antibody was raised against a 13 amino acid synthetic peptide near the center of the human Spred2. The immunogen is located within amino acids 140 - 190 of Spred2.

Isotype: IgG

Information d'application

Indications d'application: Spred2 antibody can be used for detection of Spred2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Spred2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Spred2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SPRED2

Antigène: SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

Autre désignation: Spred2 (SPRED2 Produits)

Synonymes: anticorps SPRED2, anticorps Xspred2, anticorps spred-2, anticorps Xtspred2, anticorps spred2, anticorps wu:fb93f08, anticorps zgc:77284, anticorps Spred-2, anticorps C79158, anticorps sprouty related EVH1 domain containing 2, anticorps sprouty related, EVH1 domain containing 2, anticorps sprouty-related, EVH1 domain containing 2b, anticorps sprouty-related, EVH1 domain containing 2, anticorps SPRED2, anticorps spred2, anticorps spred2b, anticorps Spred2

Sujet: Spred2 Antibody: Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.

ID gène: 200734

NCBI Accession: NP_861449

UniProt: Q7Z698