IL-17 anticorps (N-Term)
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- Antigène Voir toutes IL-17 (IL17) Anticorps
- IL-17 (IL17) (Interleukin 17 (IL17))
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Épitope
- AA 40-90, N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL-17 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- IL-17 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- IL-17 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human IL-17A. The immunogen is located within amino acids 40 - 90 of IL-17.
- Isotype
- IgG
- Top Product
- Discover our top product IL17 Anticorps primaire
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- Indications d'application
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WB: 0.125-4 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- IL-17 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- IL-17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- IL-17 (IL17) (Interleukin 17 (IL17))
- Autre désignation
- IL-17 (IL17 Produits)
- Synonymes
- anticorps CTLA8, anticorps IL-17, anticorps IL-17A, anticorps IL17, anticorps Ctla-8, anticorps Ctla8, anticorps Il17, anticorps ChIL-17, anticorps IL-17F, anticorps IL17A, anticorps CTLA-8, anticorps interleukin 17A, anticorps IL17A, anticorps Il17a
- Sujet
- IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ,B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.
- Poids moléculaire
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Predicted: 17.5kD
Observed: 20 kD (Post-modification: 1 N-linked glycosylation) kDa - ID gène
- 3605
- NCBI Accession
- NP_002181
- UniProt
- Q16552
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