IL-17 anticorps (AA 50-100)

N° du produit ABIN6991012

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-17 dans WB, ELISA, IHC (p) et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour IL-17 anticorps (AA 50-100) (ABIN6991012)

Antigène: IL-17 (IL17) (Interleukin 17 (IL17))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-17 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-IL-17 anticorps

Épitope: AA 50-100

Purification: IL-17 Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-IL-17 antibody was raised against a peptide corresponding to 16 amino acids near the center of mature human IL-17. The immunogen is located within amino acids 50-100 of IL-17.

Isotype: IgG

Information d'application

Indications d'application: WB: 0.125-2 μ,g/mL, IF: 5-20 μ,g/mL, IHC: 1-5 μ,g/mL .

Antibody validated: Western Blot in human samples, Immunofluorescence in mouse samples, Immunohistochemistry in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-17 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL-17

Antigène: IL-17 (IL17) (Interleukin 17 (IL17))

Autre désignation: IL-17

Sujet: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ,B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

Poids moléculaire: Predicted: 17.5kD

Observed: 18 kDa

ID gène: 3605

NCBI Accession: NP_002181

UniProt: Q16552