GLE1 anticorps (AA 390-440)

N° du produit ABIN6991041

Cet anticorps anti-GLE1 est un anticorps Lapin Polyclonal détectant GLE1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Rat et Souris.

Aperçu rapide pour GLE1 anticorps (AA 390-440) (ABIN6991041)

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLE1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GLE1 anticorps

Épitope: AA 390-440

Purification: Gle1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Gle1 antibody was raised against a 14 amino acid synthetic peptide near the center of human Gle1. The immunogen is located within amino acids 390 - 440 of Gle1.

Isotype: IgG

Information d'application

Indications d'application: Gle1 antibody can be used for detection of Gle1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Gle1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Gle1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur GLE1

Antigène: GLE1 (GLE1 RNA Export Mediator (GLE1))

Autre désignation: Gle1

Sujet: Gle1 Antibody: The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.

ID gène: 2733

NCBI Accession: NP_001003722

UniProt: Q53GS7