CRMP1 anticorps (N-Term)

N° du produit ABIN6991044

Cet anticorps anti-CRMP1 est un anticorps Lapin Polyclonal détectant CRMP1 dans WB, ELISA, IHC (p) et IF. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CRMP1 anticorps (N-Term) (ABIN6991044)

Antigène: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRMP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-CRMP1 anticorps

Épitope: AA 90-140, N-Term

Specificité: This antibody is expected to recognize only the longest isoform of CRMP-1.

Purification: CRMP1 Antibody is affinity chromatography purified via peptide column.

Immunogène: CRMP1 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human CRMP1. The immunogen is located within amino acids 90 - 140 of CRMP1.

Isotype: IgG

Information d'application

Indications d'application: CRMP1 antibody can be used for the detection of CRMP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CRMP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CRMP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CRMP1

Antigène: CRMP1 (Collapsin Response Mediator Protein 1 (CRMP1))

Autre désignation: CRMP1

Sujet: CRMP1 Antibody: Collapsin-response mediator proteins (CRMPs) are highly expressed in the developing brain where they play major roles in axonal outgrowth, neurite differentiation, and apoptosis. Their continued expression in areas of high synaptic remodeling such as the cerebellum, hippocampus, and the olfactory system suggests that these proteins may also be involved in adult brain plasticity. CRMP-1 was initially identified as a dihydro-pyrimidinase expressed exclusively in brain, later studies have shown that it is involved with neurotrophin (NT) 3-induced neurite formation and outgrowth. CRMP-1 localization switches from axonal to somatodendritic when neurons reach functional maturity, suggesting that it is involved in early neuronal differentiation as well as in later processes related to the survival or death of the newly generated neurons.

ID gène: 1400

NCBI Accession: NP_001014809

UniProt: Q14194