IL16 anticorps (N-Term)

N° du produit ABIN6991050

Cet anticorps anti-IL16 est un anticorps Lapin Polyclonal détectant IL16 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour IL16 anticorps (N-Term) (ABIN6991050)

Antigène: IL16 (Interleukin 16 (IL16))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL16 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL16 anticorps

Épitope: AA 140-190, N-Term

Specificité: This antibody will only detect the NIL-16 isoform.

Purification: IL-16 Antibody is affinity chromatography purified via peptide column.

Immunogène: IL-16 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human IL-16. The immunogen is located within amino acids 140 - 190 of IL-16.

Isotype: IgG

Information d'application

Indications d'application: IL-16 antibody can be used for detection of IL-16 by Western blot at 2.5 - 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-16 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: IL-16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur IL16

Antigène: IL16 (Interleukin 16 (IL16))

Autre désignation: IL-16

Sujet: IL-16 Antibody: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.

Poids moléculaire: Predicted: 145 kDa

Observed: 160 kDa

ID gène: 3603

UniProt: Q14005