IL16 anticorps (N-Term)
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- Antigène Voir toutes IL16 Anticorps
- IL16 (Interleukin 16 (IL16))
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Épitope
- AA 140-190, N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IL16 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificité
- This antibody will only detect the NIL-16 isoform.
- Purification
- IL-16 Antibody is affinity chromatography purified via peptide column.
- Immunogène
- IL-16 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human IL-16. The immunogen is located within amino acids 140 - 190 of IL-16.
- Isotype
- IgG
- Top Product
- Discover our top product IL16 Anticorps primaire
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- Indications d'application
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IL-16 antibody can be used for detection of IL-16 by Western blot at 2.5 - 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- IL-16 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- IL-16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- IL16 (Interleukin 16 (IL16))
- Autre désignation
- IL-16 (IL16 Produits)
- Synonymes
- anticorps IL16, anticorps LCF, anticorps NIL16, anticorps PRIL16, anticorps prIL-16, anticorps mKIAA4048, anticorps IL-16, anticorps interleukin 16, anticorps IL16, anticorps Il16
- Sujet
- IL-16 Antibody: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.
- Poids moléculaire
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Predicted: 145 kDa
Observed: 160 kDa - ID gène
- 3603
- UniProt
- Q14005
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