Matrilin 3 anticorps (C-Term)

N° du produit ABIN6991099

Cet anticorps Lapin Polyclonal détecte spécifiquement Matrilin 3 dans WB, ELISA et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Matrilin 3 anticorps (C-Term) (ABIN6991099)

Antigène: Matrilin 3 (MATN3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Matrilin 3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-Matrilin 3 anticorps

Épitope: AA 400-450, C-Term

Purification: MATN3 Antibody is affinity chromatography purified via peptide column.

Immunogène: MATN3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN3. The immunogen is located within amino acids 400 - 450 of MATN3.

Isotype: IgG

Information d'application

Indications d'application: MATN3 antibody can be used for detection of Matn3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MATN3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MATN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur Matrilin 3

Antigène: Matrilin 3 (MATN3)

Autre désignation: MATN3

Sujet: MATN3 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN3 is composed of a single N-terminal von Willebrand Factor A (vWFA) domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain whereas MATN1 is composed of two vWFA domains separated by one EGF-like domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that aberrant expression and processing of MATN3 are hallmarks of conventional cartilaginous neoplasms.

ID gène: 4148

UniProt: O15232