MATN1 anticorps (N-Term)

N° du produit ABIN6991104

Cet anticorps anti-MATN1 est un anticorps Lapin Polyclonal détectant MATN1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour MATN1 anticorps (N-Term) (ABIN6991104)

Antigène: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MATN1 anticorps

Épitope: AA 120-170, N-Term

Purification: MATN1 Antibody is affinity chromatography purified via peptide column.

Immunogène: MATN1 antibody was raised against a 12 amino acid synthetic peptide from near the amino terminus of human MATN1. The immunogen is located within amino acids 120 - 170 of MATN1.

Isotype: IgG

Information d'application

Indications d'application: MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MATN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MATN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MATN1

Antigène: MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))

Autre désignation: MATN1

Sujet: MATN1 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

ID gène: 4146

NCBI Accession: NP_002370

UniProt: P21941