TTR anticorps (AA 40-90)

N° du produit ABIN6991113

Cet anticorps anti-TTR est un anticorps Poulet Polyclonal détectant TTR dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TTR anticorps (AA 40-90) (ABIN6991113)

Antigène: TTR (Transthyretin (TTR))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp TTR est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TTR anticorps

Épitope: AA 40-90

Purification: Transthyretin Antibody is affinity chromatography purified via peptide column.

Immunogène: Transthyretin antibody was raised against a 17 amino acid synthetic peptide near the center of human Transthyretin. The immunogen is located within amino acids 40 - 90 of Transthyretin.

Isotype: IgY

Information d'application

Indications d'application: Transthyretin antibody can be used for detection of Transthyretin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Transthyretin Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Transthyretin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TTR

Antigène: TTR (Transthyretin (TTR))

Autre désignation: Transthyretin

Sujet: Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.

Poids moléculaire: Predicted: 15 kDa

Observed: 16 kDa

ID gène: 7276

UniProt: P02766

Pathways: Hormone Transport