PERP anticorps (C-Term)

N° du produit ABIN6991120

Cet anticorps Lapin Polyclonal détecte spécifiquement PERP dans WB, ELISA et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour PERP anticorps (C-Term) (ABIN6991120)

Antigène: PERP (TP53 Apoptosis Effector (PERP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PERP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Détail du produit anti-PERP anticorps

Épitope: C-Term

Purification: PERP Antibody is affinity chromatography purified via peptide column.

Immunogène: Anti-PERP antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human PERP. The immunogen is located within the last 50 amino acids of PERP.

Isotype: IgG

Information d'application

Indications d'application: WB: 1-2 μ,g/mL, ICC: 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PERP Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PERP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PERP

Antigène: PERP (TP53 Apoptosis Effector (PERP))

Autre désignation: PERP

Sujet: PERP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.

Poids moléculaire: Predicted: 21kD

Observed: 21 kD kDa

ID gène: 64058

NCBI Accession: NP_071404

UniProt: Q9JK95

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity