MC4R anticorps (N-Term)
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- Antigène Voir toutes MC4R Anticorps
- MC4R (Melanocortin 4 Receptor (MC4R))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MC4R est non-conjugé
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Purification
- MC4R Antibody is affinity chromatography purified via peptide column.
- Immunogène
- MC4R antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human MC4R. The immunogen is located within the first 50 amino acids of MC4R.
- Isotype
- IgG
- Top Product
- Discover our top product MC4R Anticorps primaire
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- Indications d'application
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MC4R antibody can be used for detection of MC4R by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- MC4R Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- MC4R antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- MC4R (Melanocortin 4 Receptor (MC4R))
- Autre désignation
- MC4R (MC4R Produits)
- Synonymes
- anticorps zMC4, anticorps si:dkey-151m6.62, anticorps mc4r, anticorps MC4R, anticorps LOC100218148, anticorps Mc4-r, anticorps melanocortin 4 receptor, anticorps mc4r, anticorps MC4R, anticorps Mc4r
- Sujet
- MC4R Antibody: The melanocortin-4 receptor (MC4R) is a member of the superfamily of seven transmembrane G-protein coupled receptors that are involved in multiple signal transduction pathways including the cAMP and MAPK signaling pathways. It is thought that the melanocortin system modulates energy expenditure and insulin sensitivity, activation of the MC4R results in the inhibition of c-Jun N-terminal kinase (JNK) activity and promotes insulin signaling. MC4R-null mice display maturity onset obesity characterized by hyperphagia, increased adiposity, hyperinsulinaemia and hyperleptinaemia, suggesting that like other obesity-linked genes such as FTO, PTER, and NPC1, MC4R is a potential candidate target for the treatment of obesity.
- ID gène
- 4160
- NCBI Accession
- NP_005903
- UniProt
- P32245
- Pathways
- Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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