UCMA anticorps (C-Term)
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- Antigène Voir toutes UCMA Anticorps
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
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Épitope
- C-Term
- Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp UCMA est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- UCMA Antibody is affinity chromatography purified via peptide column.
- Immunogène
- UCMA antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human UCMA. The immunogen is located within the last 50 amino acids of UCMA.
- Isotype
- IgG
- Top Product
- Discover our top product UCMA Anticorps primaire
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- Indications d'application
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UCMA antibody can be used for detection of UCMA by Western blot at 2.5 - 5 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- UCMA Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- UCMA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- UCMA (Upper Zone of Growth Plate and Cartilage Matrix Associated (UCMA))
- Autre désignation
- UCMA (UCMA Produits)
- Synonymes
- anticorps BN, anticorps GRP-10, anticorps preproGRP, anticorps proGRP, anticorps grp, anticorps GRP2, anticorps ucma, anticorps zgc:162317, anticorps C10orf49, anticorps GRP, anticorps RGD1308977, anticorps 1110017I16Rik, anticorps AW121955, anticorps Grp, anticorps GRP1, anticorps zgc:85838, anticorps gastrin releasing peptide, anticorps upper zone of growth plate and cartilage matrix associated, anticorps upper zone of growth plate and cartilage matrix associated L homeolog, anticorps upper zone of growth plate and cartilage matrix associated a, anticorps upper zone of growth plate and cartilage matrix associated b, anticorps GRP, anticorps UCMA, anticorps ucma.L, anticorps ucmaa, anticorps ucma, anticorps Ucma, anticorps ucmab
- Sujet
- UCMA Antibody: UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes. It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias. UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature. UCMA is processed by a furin-like protease into two fragments, an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C). Application of recombinant UCMA-C to primary osteoblasts, mesenchymal stem cells, and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation, but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation, suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells. At least two isoforms of UCMA are known to exist.
- Poids moléculaire
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Predicted: 15 kDa
Observed: 19 kDa - ID gène
- 221044
- NCBI Accession
- NP_660357
- UniProt
- Q8WVF2
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