PPPDE1 anticorps (C-Term)

N° du produit ABIN6991134

Cet anticorps anti-PPPDE1 est un anticorps Lapin Polyclonal détectant PPPDE1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PPPDE1 anticorps (C-Term) (ABIN6991134)

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPPDE1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PPPDE1 anticorps

Épitope: C-Term

Purification: PNAS4 Antibody is affinity chromatography purified via peptide column.

Immunogène: PNAS4 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PNAS4. The immunogen is located within the last 50 amino acids of PNAS4.

Isotype: IgG

Information d'application

Indications d'application: PNAS4 antibody can be used for detection of PNAS4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PNAS4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PNAS4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur PPPDE1

Antigène: PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))

Autre désignation: PNAS4

Sujet: PNAS4 Antibody: PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

ID gène: 51029

NCBI Accession: NP_057160

UniProt: Q9BSY9