ACBD3 anticorps (N-Term)

N° du produit ABIN6991204

Cet anticorps Lapin Polyclonal détecte spécifiquement ACBD3 dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour ACBD3 anticorps (N-Term) (ABIN6991204)

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACBD3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ACBD3 anticorps

Épitope: AA 50-100, N-Term

Purification: GOLPH1 Antibody is affinity chromatography purified via peptide column.

Immunogène: GOLPH1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human GOLPH1. The immunogen is located within amino acids 50 - 100 of GOLPH1.

Isotype: IgG

Information d'application

Indications d'application: GOLPH1 antibody can be used for detection of GOLPH1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: GOLPH1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: GOLPH1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ACBD3

Antigène: ACBD3 (Acbd3) (Acyl-CoA Binding Domain Containing 3 (Acbd3))

Autre désignation: GOLPH1

Sujet: GOLPH1 Antibody: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.

ID gène: 64746

UniProt: Q9H3P7