SRPX anticorps (N-Term)

N° du produit ABIN6991220

L’anticorps Lapin Polyclonal anti-SRPX a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter SRPX dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SRPX anticorps (N-Term) (ABIN6991220)

Antigène: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRPX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SRPX anticorps

Épitope: AA 30-80, N-Term

Purification: SRPX1 Antibody is affinity chromatography purified via peptide column.

Immunogène: SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. The immunogen is located within amino acids 30 - 80 of SRPX1.

Isotype: IgG

Information d'application

Indications d'application: SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SRPX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SRPX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SRPX

Antigène: SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

Autre désignation: SRPX1

Sujet: SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

ID gène: 8406

NCBI Accession: NP_006298

UniProt: P78539