KCNK18 anticorps (AA 210-260)

N° du produit ABIN6991251

Détail du produit anti-KCNK18 anticorps

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Épitope: AA 210-260

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNK18 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: TRESK Antibody is affinity chromatography purified via peptide column.

Immunogène: TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK. The immunogen is located within amino acids 210 - 260 of TRESK.

Isotype: IgG

Information d'application

Indications d'application: TRESK antibody can be used for detection of TRESK by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TRESK Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TRESK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KCNK18

Antigène: KCNK18 (Potassium Channel Subfamily K Member 18 (KCNK18))

Autre désignation: TRESK (KCNK18 Produits)

Synonymes: anticorps K2p18.1, anticorps MGR13, anticorps TRESK, anticorps TRESK-2, anticorps TRESK2, anticorps TRIK, anticorps Gm781, anticorps Tresk, anticorps Tresk-2, anticorps Trik, anticorps potassium two pore domain channel subfamily K member 18, anticorps potassium channel, subfamily K, member 18, anticorps KCNK18, anticorps Kcnk18

Sujet: TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

ID gène: 338567

NCBI Accession: NP_862823

UniProt: Q7Z418