BFAR anticorps (C-Term)

N° du produit ABIN6991268

Détail du produit anti-BFAR anticorps

Antigène: BFAR (Bifunctional Apoptosis Regulator (BFAR))

Épitope: AA 300-350, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BFAR est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: BFAR Antibody is affinity chromatography purified via peptide column.

Immunogène: BFAR antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human BFAR. The immunogen is located within amino acids 300 - 350 of BFAR.

Isotype: IgG

Information d'application

Indications d'application: BFAR antibody can be used for detection of BFAR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: BFAR Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: BFAR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur BFAR

Antigène: BFAR (Bifunctional Apoptosis Regulator (BFAR))

Autre désignation: BFAR (BFAR Produits)

Synonymes: anticorps BFAR, anticorps MGC137916, anticorps bfar, anticorps BAR, anticorps RNF47, anticorps 3010001A07Rik, anticorps AI666707, anticorps AW107665, anticorps Bar, anticorps Rnf47, anticorps bifunctional apoptosis regulator, anticorps bifunctional apoptosis regulator L homeolog, anticorps BFAR, anticorps bfar.L, anticorps bfar, anticorps Bfar

Sujet: BFAR Antibody: The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.

ID gène: 51283

NCBI Accession: NP_057645

UniProt: Q9NZS9