KLF4 anticorps (C-Term)

N° du produit ABIN6991274

L’anticorps Lapin Polyclonal anti-KLF4 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter KLF4 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KLF4 anticorps (C-Term) (ABIN6991274)

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KLF4 anticorps

Épitope: C-Term

Purification: KLF4 Antibody is affinity chromatography purified via peptide column.

Immunogène: KLF4 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human KLF4. The immunogen is located within the last 50 amino acids of KLF4.

Isotype: IgG

Information d'application

Indications d'application: KLF4 antibody can be used for detection of KLF4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KLF4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KLF4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KLF4

Antigène: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Autre désignation: KLF4

Sujet: KLF4 Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.

ID gène: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance