LRRC19 anticorps (C-Term)

N° du produit ABIN6991292

L’anticorps Lapin Polyclonal anti-LRRC19 a été validé pour ELISA, WB, IF et ICC. Il convient pour détecter LRRC19 dans des échantillons de Humain et Souris.

Aperçu rapide pour LRRC19 anticorps (C-Term) (ABIN6991292)

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRC19 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-LRRC19 anticorps

Épitope: AA 290-340, C-Term

Purification: LRRC19 Antibody is affinity chromatography purified via peptide column.

Immunogène: LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.

Isotype: IgG

Information d'application

Indications d'application: LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRC19 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LRRC19

Antigène: LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

Autre désignation: LRRC19

Sujet: LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κ,B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

ID gène: 64922

NCBI Accession: NP_075052

UniProt: Q9H756