MAEL anticorps (C-Term)

N° du produit ABIN6991303

Cet anticorps Lapin Polyclonal détecte spécifiquement MAEL dans ELISA, WB, IF et ICC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MAEL anticorps (C-Term) (ABIN6991303)

Antigène: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAEL est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-MAEL anticorps

Épitope: AA 30-80, C-Term

Purification: Maelstrom Antibody is affinity chromatography purified via peptide column.

Immunogène: Maelstrom antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human Maelstrom. The immunogen is located within amino acids 30 - 80 of Maelstrom.

Isotype: IgG

Information d'application

Indications d'application: Maelstrom antibody can be used for detection of Maelstrom by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Maelstrom Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: Maelstrom antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MAEL

Antigène: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Autre désignation: Maelstrom

Sujet: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.

ID gène: 84944

UniProt: Q96JY0