ANAPC11 anticorps (AA 70-120)

N° du produit ABIN6991330

Cet anticorps Lapin Polyclonal détecte spécifiquement ANAPC11 dans WB, ELISA et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour ANAPC11 anticorps (AA 70-120) (ABIN6991330)

Antigène: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC11 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-ANAPC11 anticorps

Épitope: AA 70-120

Purification: APC11 Antibody is affinity chromatography purified via peptide column.

Immunogène: APC11 antibody was raised against an 18 amino acid synthetic peptide near the center of human APC11. The immunogen is located within amino acids 70 - 120 of APC11.

Isotype: IgG

Information d'application

Indications d'application: APC11 antibody can be used for detection of APC11 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APC11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: APC11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ANAPC11

Antigène: ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))

Autre désignation: APC11

Sujet: APC11 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC11 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC11, together with APC2 and Ubc4, form the minimal APC ubiquitin ligase module.

Poids moléculaire: Predicted: 22 kDa

Observed: 22 kDa

ID gène: 51529

NCBI Accession: NP_001002244

UniProt: Q9NYG5