ANAPC13 anticorps

N° du produit ABIN6991331

Détail du produit anti-ANAPC13 anticorps

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANAPC13 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: APC13 Antibody is affinity chromatography purified via peptide column.

Immunogène: APC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13. The immunogen is located within the last 50 amino acids of APC13.

Isotype: IgG

Information d'application

Indications d'application: APC13 antibody can be used for detection of APC13 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: APC13 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: APC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ANAPC13

Antigène: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Autre désignation: APC13 (ANAPC13 Produits)

Synonymes: anticorps APC13, anticorps SWM1, anticorps 1810004D07Rik, anticorps anaphase promoting complex subunit 13, anticorps ANAPC13, anticorps Bm1_31995, anticorps LOAG_01662, anticorps Anapc13

Sujet: APC13 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.

Poids moléculaire: Predicted: 15 kDa

Observed: 14 kDa

ID gène: 25847

NCBI Accession: NP_056206

UniProt: Q9BS18