NSMCE2 anticorps (C-Term)

N° du produit ABIN6991340

L’anticorps Lapin Polyclonal anti-NSMCE2 a été validé pour WB et ELISA. Il convient pour détecter NSMCE2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NSMCE2 anticorps (C-Term) (ABIN6991340)

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NSMCE2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NSMCE2 anticorps

Épitope: AA 170-220, C-Term

Purification: MMS21 Antibody is affinity chromatography purified via peptide column.

Immunogène: MMS21 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MMS21. The immunogen is located within amino acids 170 - 220 of MMS21.

Isotype: IgG

Information d'application

Indications d'application: MMS21 antibody can be used for detection of MMS21 by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MMS21 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MMS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur NSMCE2

Antigène: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Autre désignation: MMS21

Sujet: MMS21 Antibody: MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression, this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

Poids moléculaire: Predicted: 27 kDa

Observed: 30 kDa

ID gène: 286053

NCBI Accession: NP_775956

UniProt: Q96MF7