SIRT4 anticorps (N-Term)

N° du produit ABIN6991345

Cet anticorps Poulet Polyclonal détecte spécifiquement SIRT4 dans WB et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SIRT4 anticorps (N-Term) (ABIN6991345)

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT4 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SIRT4 anticorps

Épitope: AA 80-130, N-Term

Purification: SIRT4 Antibody is affinity chromatography purified via peptide column.

Immunogène: SIRT4 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SIRT4. The immunogen is located within amino acids 80 - 130 of SIRT4.

Isotype: IgY

Information d'application

Indications d'application: SIRT4 antibody can be used for detection of SIRT4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SIRT4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SIRT4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SIRT4

Antigène: SIRT4 (Sirtuin 4 (SIRT4))

Autre désignation: SIRT4

Sujet: SIRT4 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT4 localizes to mitochondria, inhibits glutamate dehydrogenase, and is thought to be involved in the regulation of insulin secretion.

Poids moléculaire: Predicted: 37 kDa

Observed: 40 kDa

ID gène: 23409

UniProt: Q9Y6E7

Pathways: Negative Regulation of Hormone Secretion