ZEB1 anticorps (AA 530-580)

N° du produit ABIN6991365

Détail du produit anti-ZEB1 anticorps

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Épitope: AA 530-580

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZEB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Multiple isoforms of ZEB1 are known to exist.

Purification: ZEB1 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZEB1 antibody was raised against a 15 amino acid synthetic peptide near the center of human ZEB1. The immunogen is located within amino acids 530 - 580 of ZEB1.

Isotype: IgG

Information d'application

Indications d'application: ZEB1 antibody can be used for detection of ZEB1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL and immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZEB1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZEB1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZEB1

Antigène: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Autre désignation: ZEB1 (ZEB1 Produits)

Synonymes: anticorps ZFH/[d]EF1, anticorps kheper, anticorps zeb1, anticorps zfhx1, anticorps bzp, anticorps zeb, anticorps tcf8, anticorps areb6, anticorps nil2a, anticorps zfhep, anticorps nil-2a, anticorps zfhx1a, anticorps nil-2-a, anticorps MGC97552, anticorps TCF8, anticorps AREB6, anticorps BZP, anticorps DELTAEF1, anticorps FECD6, anticorps NIL2A, anticorps PPCD3, anticorps ZFHEP, anticorps ZFHX1A, anticorps 3110032K11Rik, anticorps MEB1, anticorps Nil2, anticorps TCF-8, anticorps Tcf18, anticorps Tcf8, anticorps Tw, anticorps ZEB, anticorps Zfhep, anticorps Zfhx1a, anticorps Zfx1a, anticorps Zfx1ha, anticorps [delta]EF1, anticorps deltaEF1, anticorps deltaef1, anticorps fecd6, anticorps zinc finger E-box binding homeobox 1b, anticorps zinc finger E-box binding homeobox 1, anticorps zinc finger E-box binding homeobox 1 S homeolog, anticorps zeb1b, anticorps zeb1, anticorps ZEB1, anticorps Zeb1, anticorps zeb1.S

Sujet: ZEB1 Antibody: ZEB1, initially identified as the delta-crystallin enhancer binding protein delta EF1, is a DNA-binding protein that binds to a modified E-box sequence and has been implicated in postgastrulation embryogenesis. ZEB1 binds to the promoter of several hemapoietic genes, including interleukin-2, CD4, GATA-3, and alpha-integrin, and mice in which ZEB1 has been targeted show thymic atrophy, and severe defects in lymphocyte differentiation. Recent evidence suggests that ZEB1 also regulates the accumulation of adipose tissue and may play a role in obesity. Mutations in this gene have been associated with late-onset Fuchs endothelial corneal dystrophy.

Poids moléculaire: Predicted: 124 kDa

Observed: 130 kDa

ID gène: 6935

NCBI Accession: NP_110378

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation