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TCTN1 anticorps (N-Term)

TCTN1 Reactivité: Humain, Souris WB, ELISA, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6991369
  • Antigène Voir toutes TCTN1 Anticorps
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Épitope
    • 15
    • 2
    • 1
    AA 30-80, N-Term
    Reactivité
    • 16
    • 3
    • 2
    Humain, Souris
    Hôte
    • 18
    Lapin
    Clonalité
    • 18
    Polyclonal
    Conjugué
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TCTN1 est non-conjugé
    Application
    • 18
    • 13
    • 13
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    TCTN1 Antibody is affinity chromatography purified via peptide column.
    Immunogène
    TCTN1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TCTN1. The immunogen is located within amino acids 30 - 80 of TCTN1.
    Isotype
    IgG
    Top Product
    Discover our top product TCTN1 Anticorps primaire
  • Indications d'application
    TCTN1 antibody can be used for detection of TCTN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    TCTN1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,4 °C
    Stockage commentaire
    TCTN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    TCTN1 (Tectonic Family Member 1 (TCTN1))
    Autre désignation
    TCTN1 (TCTN1 Produits)
    Synonymes
    anticorps FLJ21127, anticorps JBTS13, anticorps TECT1, anticorps G730031O11Rik, anticorps Tect1, anticorps RGD1566266, anticorps tectonic family member 1, anticorps tectonic family member 1 L homeolog, anticorps TCTN1, anticorps tctn1.L, anticorps tctn1, anticorps Tctn1
    Sujet
    TCTN1 Antibody: TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
    ID gène
    79600
    NCBI Accession
    NP_001076007
    UniProt
    Q2MV58
    Pathways
    Tube Formation
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