TCTN2 anticorps (C-Term)

N° du produit ABIN6991370

L’anticorps Lapin Polyclonal anti-TCTN2 a été validé pour WB et ELISA. Il convient pour détecter TCTN2 dans des échantillons de Humain et Souris.

Aperçu rapide pour TCTN2 anticorps (C-Term) (ABIN6991370)

Antigène: TCTN2 (Tectonic Family Member 2 (TCTN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCTN2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TCTN2 anticorps

Épitope: AA 610-660, C-Term

Purification: TCTN2 Antibody is affinity chromatography purified via peptide column.

Immunogène: TCTN2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TCTN2. The immunogen is located within amino acids 610 - 660 of TCTN2.

Isotype: IgG

Information d'application

Indications d'application: TCTN2 antibody can be used for detection of TCTN2 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TCTN2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TCTN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TCTN2

Antigène: TCTN2 (Tectonic Family Member 2 (TCTN2))

Autre désignation: TCTN2

Sujet: TCTN2 Antibody: TCTN2 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN2 is not known, it is 49 % similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

ID gène: 79867

NCBI Accession: NP_079085

UniProt: Q96GX1

Pathways: Proton Transport