CABP7 anticorps (N-Term)

N° du produit ABIN6991381

Cet anticorps Lapin Polyclonal détecte spécifiquement CABP7 dans WB, ELISA, ICC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CABP7 anticorps (N-Term) (ABIN6991381)

Antigène: CABP7 (Calcium Binding Protein 7 (CABP7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CABP7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-CABP7 anticorps

Épitope: N-Term

Purification: CaBP7 Antibody is affinity chromatography purified via peptide column.

Immunogène: CaBP7 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CaBP7. The immunogen is located within the first 50 amino acids of CaBP7.

Isotype: IgG

Information d'application

Indications d'application: CaBP7 antibody can be used for detection of CaBP7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CaBP7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CaBP7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CABP7

Antigène: CABP7 (Calcium Binding Protein 7 (CABP7))

Autre désignation: CaBP7

Sujet: CaBP7 Antibody: Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70 % homology with CaBP8 and 50 % homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

ID gène: 164633

NCBI Accession: NP_872333

UniProt: Q86V35