CCDC106 anticorps (C-Term)

N° du produit ABIN6991384

Cet anticorps Lapin Polyclonal détecte spécifiquement CCDC106 dans ELISA, WB, IHC (p) et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CCDC106 anticorps (C-Term) (ABIN6991384)

Antigène: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCDC106 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-CCDC106 anticorps

Épitope: C-Term

Purification: CCDC106 Antibody is affinity chromatography purified via peptide column.

Immunogène: CCDC106 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106. The immunogen is located within the last 50 amino acids of CCDC106.

Isotype: IgG

Information d'application

Indications d'application: CCDC106 antibody can be used for detection of CCDC106 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CCDC106 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CCDC106 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CCDC106

Antigène: CCDC106 (Coiled-Coil Domain Containing 106 (CCDC106))

Autre désignation: CCDC106

Sujet: CCDC106 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

ID gène: 29903

NCBI Accession: NP_037433

UniProt: Q9BWC9