CRISP2 anticorps (N-Term)

N° du produit ABIN6991388

Détail du produit anti-CRISP2 anticorps

Antigène: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRISP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: CRISP2 Antibody is affinity chromatography purified via peptide column.

Immunogène: CRISP2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2. The immunogen is located within the first 50 amino acids of CRISP2.

Isotype: IgG

Information d'application

Indications d'application: CRISP2 antibody can be used for detection of CRISP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CRISP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CRISP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CRISP2

Antigène: CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))

Autre désignation: CRISP2 (CRISP2 Produits)

Synonymes: anticorps ct36, anticorps tpx1, anticorps tsp1, anticorps crisp, anticorps gapdl5, anticorps crisp-2, anticorps CRISP3, anticorps CRISP2, anticorps CRISP-2, anticorps GAPDL5, anticorps Tpx-1, anticorps Tpx1, anticorps Crisp2l, anticorps CT36, anticorps TPX1, anticorps TSP1, anticorps CRISP-3, anticorps CRISP-1, anticorps Crisp2, anticorps cysteine-rich secretory protein 2 L homeolog, anticorps cysteine rich secretory protein 2, anticorps cysteine-rich secretory protein 2, anticorps crisp2.L, anticorps CRISP2, anticorps Crisp2

Sujet: CRISP2 Antibody: The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.

ID gène: 7180

NCBI Accession: NP_001135880

UniProt: P16562