KPNA3 anticorps

N° du produit ABIN6991415

L’anticorps Lapin Polyclonal anti-KPNA3 a été validé pour WB, ELISA, IF et ICC. Il convient pour détecter KPNA3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KPNA3 anticorps (ABIN6991415)

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-KPNA3 anticorps

Purification: KPNA3 Antibody is affinity chromatography purified via peptide column.

Immunogène: KPNA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy end of human KPNA3. The immunogen is located within the last 50 amino acids of KPNA3.

Isotype: IgG

Information d'application

Indications d'application: KPNA3 antibody can be used for detection of KPNA3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KPNA3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KPNA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KPNA3

Antigène: KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))

Autre désignation: KPNA3

Sujet: KPNA3 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.

ID gène: 3839

NCBI Accession: NP_002258

UniProt: O00505

Pathways: Protein targeting to Nucleus