MFSD2A anticorps (C-Term)

N° du produit ABIN6991432

Détail du produit anti-MFSD2A anticorps

Antigène: MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFSD2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: MFSD2A Antibody is affinity chromatography purified via peptide column.

Immunogène: MFSD2A antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human MFSD2A. The immunogen is located within the last 50 amino acids of MFSD2A.

Isotype: IgG

Information d'application

Indications d'application: MFSD2A antibody can be used for detection of MFSD2A by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human, mouse, and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: MFSD2A Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: MFSD2A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur MFSD2A

Antigène: MFSD2A (Major Facilitator Superfamily Domain Containing 2A (MFSD2A))

Autre désignation: MFSD2A (MFSD2A Produits)

Synonymes: anticorps 1700018O18Rik, anticorps Mfsd2, anticorps RGD1310174, anticorps MFSD2, anticorps NLS1-A, anticorps Sodium-dependent LPC symporter 1-A, anticorps mfsd2a, anticorps zgc:101615, anticorps mfsd2, anticorps NLS1-B, anticorps Sodium-dependent LPC symporter 1-B, anticorps mfsd2b, anticorps zgc:101069, anticorps major facilitator superfamily domain containing 2A, anticorps major facilitator superfamily domain containing 2aa, anticorps major facilitator superfamily domain containing 2A L homeolog, anticorps major facilitator superfamily domain containing 2ab, anticorps MFSD2A, anticorps mfsd2a, anticorps Mfsd2a, anticorps mfsd2aa, anticorps mfsd2a.L, anticorps mfsd2ab

Sujet: MFSD2A Antibody: Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.

ID gène: 492810

NCBI Accession: NP_001129965

UniProt: Q5U3U7