SYNPO anticorps (C-Term)

N° du produit ABIN6991442

L’anticorps Lapin Polyclonal anti-SYNPO a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter SYNPO dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SYNPO anticorps (C-Term) (ABIN6991442)

Antigène: SYNPO (Synaptopodin (SYNPO))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNPO est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SYNPO anticorps

Épitope: C-Term

Specificité: At least three isoforms of SYNPO are known to exist, this antibody will detect all three isoforms. SYNPO antibody is predicted to not cross-react with other SYNPO family member proteins.

Purification: SYNPO Antibody is affinity chromatography purified via peptide column.

Immunogène: SYNPO antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SYNPO. The immunogen is located within the last 50 amino acids of SYNPO.

Isotype: IgG

Information d'application

Indications d'application: SYNPO antibody can be used for detection of SYNPO by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYNPO Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SYNPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SYNPO

Antigène: SYNPO (Synaptopodin (SYNPO))

Autre désignation: SYNPO

Sujet: SYNPO Antibody: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.

Poids moléculaire: Predicted: 75, 99, 102 kDa

Observed: 95 kDa

ID gène: 11346

NCBI Accession: NP_001159680

UniProt: Q8N3V7