SYNPO2 anticorps (N-Term)

N° du produit ABIN6991443

Détail du produit anti-SYNPO2 anticorps

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Épitope: AA 320-370, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNPO2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: SYNPO2 Antibody is affinity chromatography purified via peptide column.

Immunogène: SYNPO2 antibody was raised against a 20 amino acid synthetic peptide near the amino terminus of human SYNPO2. The immunogen is located within amino acids 320 - 370 of SYNPO2.

Isotype: IgG

Information d'application

Indications d'application: SYNPO2 antibody can be used for detection of SYNPO2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: SYNPO2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: SYNPO2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SYNPO2

Antigène: SYNPO2 (Synaptopodin 2 (SYNPO2))

Autre désignation: SYNPO2 (SYNPO2 Produits)

Synonymes: anticorps SYNOP2, anticorps RGD1564779, anticorps 1110069I04Rik, anticorps 2310068J10Rik, anticorps 9530006G20Rik, anticorps AI848603, anticorps Myo, anticorps synaptopodin 2, anticorps synaptopodin-2, anticorps SYNPO2, anticorps LOC100484043, anticorps Synpo2

Sujet: SYNPO2 Antibody: SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.

ID gène: 171024

NCBI Accession: NP_597734

UniProt: Q9UMS6