TMEM59 anticorps (N-Term)

N° du produit ABIN6991448

L’anticorps Lapin Polyclonal anti-TMEM59 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter TMEM59 dans des échantillons de Humain.

Aperçu rapide pour TMEM59 anticorps (N-Term) (ABIN6991448)

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TMEM59 anticorps

Épitope: AA 80-130, N-Term

Purification: TMEM59 Antibody is affinity chromatography purified via peptide column.

Immunogène: TMEM59 antibody was raised against a 16 amino acid synthetic peptide near amino terminus of human TMEM59. The immunogen is located within amino acids 80 - 130 of TMEM59.

Isotype: IgG

Information d'application

Indications d'application: TMEM59 antibody can be used for detection of TMEM59 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TMEM59 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TMEM59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TMEM59

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Autre désignation: TMEM59

Sujet: TMEM59 Antibody: Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

ID gène: 9528

NCBI Accession: NP_004863

UniProt: Q9BXS4