CTNNBL1 anticorps (C-Term)

N° du produit ABIN6991497

Cet anticorps anti-CTNNBL1 est un anticorps Lapin Polyclonal détectant CTNNBL1 dans WB, ELISA, IF et IHC (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour CTNNBL1 anticorps (C-Term) (ABIN6991497)

Antigène: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTNNBL1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CTNNBL1 anticorps

Épitope: C-Term

Specificité: CTNNBL1 antibody is predicted to not cross-react with other catenin family members. At least four isoforms of CTNNBL1 are known to exist, this antibody will detect all but isoform b.

Purification: CTTNBL1 Antibody is affinity chromatography purified via peptide column.

Immunogène: CTTNBL1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human CTTNBL1. The immunogen is located within the last 50 amino acids of CTTNBL1.

Isotype: IgG

Information d'application

Indications d'application: CTTNBL1 antibody can be used for detection of CTTNBL1 by Western blot at 1 and 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CTTNBL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CTTNBL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur CTNNBL1

Antigène: CTNNBL1 (Catenin, beta Like 1 (CTNNBL1))

Autre désignation: CTTNBL1

Sujet: CTTNBL1 Antibody: The Beta-catenin-like protein 1 (CTNNBL1) contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs, as well as Armadillo/beta-catenin-like repeats. Transient expression of CTNNBL1 resulted in translocation to the nucleus and apoptosis, suggesting it may be involved in the apoptotic pathway. CTNNBL1 interacts with the Prp19 complex of the spliceosome and the Ig class switching enzyme activation-induced deaminase (AID) and had been suggested to play a role in antibody-diversification and class switching, but recent studies have shown CTNNBL1 to be dispensable for Ig class switch recombination. Other studies have identified CTTNBL1 as a novel gene for obesity.

Poids moléculaire: Predicted: 65 kDa

Observed: 63 kDa

ID gène: 56259

NCBI Accession: NP_110517

UniProt: Q8WYA6

Pathways: Production of Molecular Mediator of Immune Response